Akat Mah. Gül Sok. 1. Söltaş Evleri No:11 · Beşiktaş Mon–Fri 10:00–18:00 · Sat 10:00–17:00
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Knee Area Lipolysis

Knee area lipolysis is a targeted, non-surgical treatment that aims to reduce stubborn fat around the kneecap, especially on the inner side – a concern many people have regardless of their overall…

3 min read Updated: 28 October 2026 Dr. Selin Zehra Uçar
Knee Area Lipolysis
On this page
  1. A Key Point of Leg Aesthetics: Why Does Fat Collect Around the Knees?
  2. Knee Area Lipolysis
  3. Completing the Leg Silhouette

Knee area lipolysis is a targeted, non-surgical treatment that aims to reduce stubborn fat around the kneecap, especially on the inner side – a concern many people have regardless of their overall weight. However shapely and toned the legs are, localised fat around the knees can make them look shorter, thicker and less elegant, and affect confidence when wearing skirts, shorts or fitted trousers.

Where diet and exercise fall short in this specific area, lipolysis – breaking down and dissolving fat cells – can be an effective solution. It requires no surgery, is done in short sessions and allows an immediate return to social life. The aim is a smooth, uninterrupted leg line. At our clinic in Beşiktaş, Istanbul, I plan each treatment individually.

A Key Point of Leg Aesthetics: Why Does Fat Collect Around the Knees?

When looking at the legs as a whole, the knees are one of the most important balancing points: a smooth, proportionate knee without fat deposits makes the leg look longer and more elegant. The main reason fat collects here lies in genetics and hormones. Like the hips or abdomen, some areas of the body are genetically programmed to store fat, and the area around the knee – especially the inner (medial) knee – is one of them. So even people at their ideal weight, or slim, can have thickness and fat around the knees.

This is largely outside a person’s control. Leg exercises such as squats and lunges tone the muscles but do little to reduce the fat on top of them, which can be very frustrating. Surgical fat removal from the knee carries risks, anaesthesia and recovery time, so a non-surgical method such as knee lipolysis is a more practical option for many people.

Knee Area Lipolysis

Knee area lipolysis is an injection-based treatment for slimmer, more defined, smoother knees. It targets localised fat pads above the kneecap and on its inner sides that disrupt the leg’s silhouette. Without incisions, stitches or anaesthesia, it is quick enough to fit into a lunch break.

The Art of Micro-Injection: A Scientific Approach to Fat Cells

At the heart of the treatment are phosphatidylcholine (PPC), derived from soya lecithin, and deoxycholate, a bile acid, combined in a special formulation. The solution is injected through micro-needles almost as fine as a hair into precisely planned points in the fat around the knee. Working on a small, curved area close to bone like the knee requires great precision and anatomical knowledge.

Deoxycholate dissolves and breaks down the fat cell membrane like a detergent, releasing the stored fat (triglycerides) into the space between cells. PPC then breaks these fat droplets into much smaller particles, making them easier to remove. The lymphatic system collects the debris and carries it to the liver, where it is metabolised – used for energy or eliminated. Because fat cells are destroyed rather than simply shrunk, results are long-lasting as long as you do not gain significant weight.

Completing the Leg Silhouette

I look at the knee not in isolation but as part of the whole leg. At the first consultation I try to understand exactly what bothers you: the fat pad on the inner knee, or the slight bulge just above the kneecap? I then assess the whole leg – thigh, knee and lower leg – so that the result is in harmony with the rest of your leg.

A personal treatment plan then sets out the number of sessions and the points, angle and depth of the injections. Careful, fine technique suited to the knee’s delicate, curved structure helps achieve a smooth, natural result and minimise bruising and swelling. As with other lipolysis treatments, temporary swelling, tenderness and bruising are common after sessions, and results appear gradually over the following weeks. I also give advice afterwards to help you maintain the result. Results vary between individuals, and the use of these solutions on the body may be off-label in some countries; I will discuss the products used with you.

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We will assess together whether it suits you.

This page is for general information. Suitability, possible side effects and expected results are assessed at a medical consultation; results vary between individuals.

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AddressAkat Mah. Gül Sok. 1. Söltaş Evleri No:11, 34335 Beşiktaş / İstanbul
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